The U.S. Food and Drug Administration has approved ocrelizumab (Ocrevus) for the treatment of adult patients with relapsing forms of multiple sclerosis, and for primary-progressive MS. Ocrelizumab is a humanized monoclonal antibody that targets CD20+ B cells. It is the first disease-modifying therapy to be approved for PPMS. The FDA had given ocrelizumab breakthrough therapy and fast track designations, and granted it a priority review. Read More