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Inappropriate prescribing common in AD patients

November 13, 2013

…edication (PIM) use in 684 patients with mild-to-moderate AD living in the community (Montastruc et al. Eur J Clin Pharmacol 2013;69:1589-1597). Overall, 46.8% of subjects had received at least one PIM. The most common PIMs were cerebral vasodilators (24% of all prescriptions), atropinic drugs (17%) and long half-life benzodiazepines (8.5%). In 16% of cases, atropinic agents were given in conjunction with cholinesterase inhibitors. At risk of PIMs…

New review of PD pathophysiology

September 11, 2013

…ers may find useful for teaching purposes. Free full text is available at: www.frontiersin.org/Neurodegeneration/10.3389/fneur.2013.00033/abstract. Comment Dr. Michel Panisset: Although the cause for Parkinson’s disease is still unknown, new data are helping to open up new avenues for investigations, e.g. gastrointestinal involvement, increased absorption and mesenteric plexus Lewy bodies, and the prion-like behavior of alpha-synuclein. Finding th…

Guidelines on managing bipolar disorder: CANMAT 2013 update

September 11, 2013

The Canadian Network for Mood and Anxiety Disorders (CANMAT) has produced an update of its guidelines for the management of patients with bipolar disorder (Yatham et al. Bipolar Disord 2013;15:1-44). The guidelines were produced in conjunction with the International Society for Bipolar Disorders. Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Cont…

Optimizing treatment of RRMS: Canadian recommendations

September 4, 2013

SPECIAL REPORT The Canadian MS Working Group has issued recommendations on optimizing treatment of patients with relapsing-remitting MS (Freedman et al. Can J Neurol Sci 2013;40:307-323). The publication updates recommendations published in 2004 (Freedman et al. Can J Neurol Sci 2004;31:157-168). See below for free download information. Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address tha…

Who prescribes DMTs for MS?

June 5, 2013

…An analysis of an Ontario claims database shows that a small proportion of neurologists prescribe most of the disease-modifying therapies (DMTs) for MS (Marriott et al. Can J Neurol Sci 2013;40:67-72). Overall, 80% of DMT prescriptions were written by 12% of the neurologist community. Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…