…elapses, sphincteric symptoms, multifocal symptoms, relapse severity and incomplete recovery (Bergamaschi et al. J Neurol Sci 2001;189:13-21; Leone et al. Mult Scler 2008;14:485-493). Relapse frequency also has had prognostic significance in some studies (Hirst et al. J Neurol 2008;255:280-287). However, the UBC group found that although one or more relapses in the first five years post-diagnosis was important, the number of relapses became less i…

…hree anti-EBV antibodies: anti-EBV nuclear antigen 1 (anti-EBNA-1) or EBNA complex; antiviral capsid antigen (anti-VCA); and anti-Early Antigen (anti-EA). The median seroprevalence of anti-EBNA IgG was 98% in MS patients compared to 88% in controls (odds ratio 4.7). The median anti-VCA IgG seropositivity was 99% in MS patients versus 92% in controls (OR 4.51). In contrast, the median seroprevalence for anti-EA IgG was similar in cases and controls…