…oke in PD patients (Huang et al. PLoS One 2013;8:e68314; free full text at www.ncbi.nlm.nih.gov/pmc/articles/pmid/24023710/). The study compared 2,204 PD patients and the same number of propensity score-matched subjects. At three-year follow-up, there were 328 ischemic strokes in the PD group compared to 156 strokes in the non-PD group (HR 2.37). It is unclear why PD patients have an increased risk of MI and stroke and further study is needed to e…

…kely to be treated or that current therapies are only partially effective. Comment Dr. Susan Fox: This large multicentre study shows that depression is common in PD. The importance of this report is that the evidence was gathered from patients and caregivers, not physicians, and shows a disconnect between the two. Physicians need to ask about depression at every visit. Treating PD depression can be challenging due to concerns about side effects of…