Patients with Parkinson’s disease have a significantly elevated risk of acute myocardial infarction and cardiovascular death, according to a population-based longitudinal study (Liang et al. Am Heart J 2015;169:508-514). The analysis included 3,211 PD patients and 3,211 propensity score-matched subjects without PD. During the three-year follow-up, there were 83 fatal or non-fatal AMIs in the PD group compared to 53 in the non-PD group (hazard ratio 1.67). There were also significant differences in the PD versus non-PD groups for the combined endpoint of AMI or cardiovascular death (HR 1.46), and for AMI or all-cause mortality (HR 1.42).