Health Canada has approved cladribine tablets for the treatment of adults with relapsing-remitting multiple sclerosis (RRMS), to reduce the frequency of clinical exacerbations and delay the progression of disability. The drug, marketed as Mavenclad, may be used for newly-diagnosed patients, but is generally recommended in MS patients with an inadequate response or poor tolerability to a prior MS therapy. Read More
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Cladribine tablets – Updated efficacy and safety results
November 28, 2017Cladribine tablets, a novel intermittent immunosuppressant expected soon in North America, has been shown to be highly efficacious in reducing annualized relapse rates (ARR) and disability progression over a sustained period, according to the most recent data. Read More
ECTRIMS 2017 SLIDE DECK
November 9, 2017Selected highlights of ECTRIMS – ACTRIMS 2017
Paris, France – 25-28 October 2017
34 slides
Click here to download the ECTRIMS 2017 Slide Deck
Scientific review:
Dr. Daniel Selchen, Chief of Neurology, St. Michael’s Hospital, Toronto, Canada
Emerging Treatment Goals in Schizophrenia – Toward Functional Recovery
November 3, 2017SPECIAL REPORT
Comment by Dr. Ofer Agid
Comment by Dr. Ashok Malla
The management of schizophrenia has traditionally focussed on a reduction in positive and negative symptoms with antipsychotic agents. However, this narrow focus does not adequately address other features that are important to patients and caregivers, such as social and occupational functioning, involvement in productive activities, and an ability to live independently. When the European Group on Functional Outcomes and Remission in Schizophrenia (EGOFORS) examined how psychiatrists, patients and caregivers viewed symptomatic remission, only 18% agreed in their assessment (Karow et al. Eur Psychiatry 2012;27:426-431). For clinicians, remission was largely defined as improvement in PANSS scores; whereas for patients, remission was characterized by good subjective well-being, and for caregivers it was a combination of improved well-being and symptom reduction.