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ECTRIMS/EAN publish new MS treatment guidelines

 

The European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) and the European Academy of Neurology (EAN) have published new guidelines on the use of disease-modifying drugs (DMDs) for multiple sclerosis (Montalban et al. Mult Scler 2018; epublished January 1, 2018; free full text at http://journals.sagepub.com/doi/pdf/10.1177/1352458517751049). The groups identified 10 key questions, and issued a series of recommendations based on the level of evidence.

The following is a summary of the groups’ recommendations. Read More

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Vortioxetine: Improved work productivity in adults with major depression

 

SPECIAL REPORT

Comment by Dr. Pratap Chokka, Edmonton, Alberta

Antidepressant therapies have traditionally been evaluated for their effect on symptoms of depression and anxiety. However, symptomatic improvements may not result in functional gains in areas such as work performance and productivity, activities of daily living and quality of life. In the latest iteration of the Canadian Network for Mood and Anxiety Treatments (CANMAT) clinical guidelines for the management of major depressive disorder (MDD), functional recovery was recognized as a priority in the treatment of MDD in both the acute and maintenance phases of the disease (Lam et al. Ann Clin Psychiatry 2015;27:142-149). The group concluded that there was a need for evidence-based interventions that demonstrated an improvement in patient functioning. Read More