Heart disease associated with atrophy in MS


The University of Buffalo MS group has reported that comorbid cardiovascular disease appears to contribute to more rapid brain tissue loss in patients with multiple sclerosis (Jakimovski et al. Eur J Neurol 2018; epublished August 13, 2018).

The study compared 194 MS patients and 43 healthy controls over a 5-year period. Brain atrophy was evaluated with 3T MRI. MS patients with cardiovascular disease had a higher loss of white matter volume (-4.2% vs. -0.7%) and whole-brain volume (-3.4% vs. -1.6%) compared to MS patients without heart disease.

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