…Includes data on NfL changes after initiation of fingolimod, ofatumumab, ocrelizumab, natalizumab, alemtuzumab and oral cladribine. 11 slides Download the slide deck…
…Click here to listen to a NeuroSound podcast with lead author Dr. Paul Giacomini. Clinical tip of the day Anti-CD20 therapy in the months before pregnancy is associated with a lower relapse rate in the pregnancy/postpartum period compared to prior treatment with natalizumab or fingolimod (Sahloul et al. ECTRIMS/ACTRIMS 2023;P062). An analysis of 66 consecutive pregnancies also reported that MRI activity during pregnancy/postpartum occurred in 5.2…
…, suggesting that de-escalation may be appropriate in some older patients. Comparing high-efficacy DMTs Two studies reported a variety of methods to indirectly compare the efficacy of DMTs in RMS. The first study conducted a propensity score analysis of data from the ASCLEPIOS I/II trials of ofatumumab and the FREEDOMS I/II and TRANSFORMS trials of fingolimod (Butzkueven et al. ECTRIMS/ACTRIMS 2023;P755). Ofatumumab was superior to fingolimod with…
…-tracking software (de Villers-Sidani et al. Front Neurol 2023;14:1243594). Click here to access the full paper online or download the pdf….
…ssing immunoglobulins (7.69%), or recommending regular vaccinations for influenza, pneumonia and COVID-19 (7.60%). A majority of respondents (84.62%) would recommend all of the above measures. View the video commentary from Dr. Virginia Devonshire….