The total area of a carotid plaque appears to be a stronger predictor for a first ischemic stroke than intima-medial thickness (IMT), according to an analysis from the 10-year longitudinal Tromso study (Mathiesen et al. Stroke 2011; 42: 972-978).
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Anxiety associated with cortical atrophy in AD
July 6, 2011REPORT FROM THE AMERICAN ACADEMY OF NEUROLOGY (AAN) 63RD ANNUAL MEETING, HONOLULU, HAWAII, APRIL 9-16, 2011 – Symptoms of anxiety may be associated with atrophy in discrete brain regions in mild AD patients, according to the most recent report from the Alzheimer Disease Neuroimaging Initiative (Poulin et al. AAN 2011; abstract P06.188).
ECG abnormalities may be PD risk factor
July 6, 2011REPORT FROM THE AMERICAN ACADEMY OF NEUROLOGY (AAN) 63RD ANNUAL MEETING, HONOLULU, HAWAII, APRIL 9-16, 2011 – An analysis of subjects in the Cardiovascular Health Study in the U.S. has reported that electrocardiographic abnormalities may be a risk factor for Parkinson’s disease (Jain et al. AAN 2011; abstract S03.004). This is the first reported link between ECG findings and PD risk.
Traumatic brain injury: no effect on AD phenotype
July 6, 2011REPORT FROM THE AMERICAN ACADEMY OF NEUROLOGY (AAN) 63RD ANNUAL MEETING, HONOLULU, HAWAII, APRIL 9-16, 2011 – The possible link between Alzheimer’s disease and a history of traumatic brain injury is unclear (for a review see Jellinger KA. Curr Opin Neurol 2004; 17: 719-723). This issue was examined in a retrospective analysis of pathology data for the period 1997 to 2010 (Mehta et al. AAN 2011; abstract P07.244). Traumatic brain injury was defined as a closed head injury with loss of consciousness. The study sample included 108 subjects with AD, of whom 11 had a history of brain injury.