The first meta-analysis of the effect of antidepressants on body weight has found that mirtazapine, paroxetine and amitriptyline are associated with a greater risk of weight gain (Serretti & Mandelli. J Clin Psychiatry 2010; 71: 1259-1272). Fluoxetine and bupropion were associated with some weight loss.
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Deep brain stimulation: consensus recommendations
March 9, 2011An international consortium has published its recommendations on issues relating to deep brain stimulation (DBS) in patients with Parkinson’s disease (Bronstein et al. Arch Neurol 2010; epublished October 11, 2010).
White matter hyperintensities predict cognitive decline
February 23, 2011White matter hyperintensities are a predictor of cognitive decline in relatively healthy older subjects, according to data from the Alzheimer Disease Neuroimaging Initiative (Carmichael et al. Arch Neurol 2010; 67: 1370-1378).
MoCA recommended to detect cognitive dysfunction in Parkinson’s disease
February 23, 2011The task force of the Parkinson Study Group Cognitive/Psychiatric Working Group has recommended the Montreal Cognitive Assessment (MoCA) as the most suitable tool to detect mild cognitive impairment (MCI) in patients with Parkinson’s disease (Chou et al. Mov Disord 2010; 25: 2501-2507). The task force further recommended that the MoCA be employed in clinical trials of PD where the primary outcome is not cognitive performance.