Olfactory deficits a biomarker of Alzheimerβs disease?
April 22, 2015…eriod, 36.4% of aMCI patients with impaired olfaction developed AD, compared to 17.3% of aMCI patients with intact olfaction. The ROC AUC for conversion to AD was 0.62, which the authors noted is comparable to CSF biomarkers such as beta-amyloid42, tau and p-tau. Thus, impaired olfaction may be an easily administered, low-cost tool for stratifying the risk of conversion from aMCI to AD. Guest Reviewer: Dr. Daniel Selchen, Head of Neurology, St. Mi…