A new meta-analysis has concluded that deep-brain stimulation (DBS) is effective in the control of motor signs and for improving functionality and quality of life in patients with Parkinson’s disease (Perestelo-Perez et al. J Neurol 2014; epublished February 2, 2014). Data were analysed from six randomized controlled trials comparing DBS with medication versus medications alone (n=1184).
The outcome measures included motor function, time without dyskinesias, reduction in levodopa-equivalent dosing, neurocognitive and psychiatric effects, and effect on quality of life. Read More