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Cognitive dysfunction in pediatric- vs. adult-onset MS

 

REPORT FROM THE ACTRIMS-ECTRIMS – BOSTON, MA, SEPTEMBER 10-13, 2014 – Cognitive outcomes appear to be similar in pediatric-onset MS and adult-onset MS despite a longer disease duration in younger patients (Hakiki et al. ECTRIMS 2014; abstract YI2.3).

Neuropsychological performance was assessed with the Rao Brief Repeatable Battery and the Stroop test in 14 patients with a history of pediatric-onset MS and 30 age-matched adult RRMS patients. Duration of MS was 9.8 years and 3.7 years, respectively. Mean EDSS score was 1.7 and 1.5. Mean age for the two groups was 26 years. Read More

Spinal taps prognostic in CIS

 

REPORT FROM THE ACTRIMS-ECTRIMS – BOSTON, MA, SEPTEMBER 10-13, 2014 – Testing for oligoclonal Ig bands in cerebrospinal fluid is useful in predicting which patients with clinically isolated syndrome (CIS) are at risk of developing clinically-definite MS (Tumani et al. ECTRIMS 2014; abstract P197). Read More

Trend to earlier, more aggressive therapy: U.S. survey

 

REPORT FROM THE ACTRIMS-ECTRIMS – BOSTON, MA, SEPTEMBER 10-13, 2014 – A U.S. survey of academic and community neurologists from the Consortium of Multiple Sclerosis Centers (CMSC) reports that clinicians tend to favour an earlier, more aggressive treatment approach (Tornatore et al. ECTRIMS 2014; abstract P295). Read More

Novel theory proposed for AD

 

Researchers in Texas have proposed that vascular activation contributes to the pathogenesis of Alzheimer’s disease, resulting in the overexpression of amyloid-beta and other factors (Grammas et al. J Alzheimers Dis 2014;40:619-630).       Read More

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