Neurology

No unfavourable effects of fasting in MS

 

A study in Iran has examined the effect of prolonged fasting during Ramadan in adult MS patients (Saadatnia et al. Eur Neurol 2009; 61:230-232). The prospective study compared 40 MS patients who fasted with 40 non-fasting MS controls. All patients had mild disability at entry (EDSS score < 3). Clinical symptoms and EDSS changes were assessed in the 6 months following Ramadan.

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Randomized trial of donepezil in MCI

 

Cholinesterase inhibitors may produce small improvements in cognitive functioning in patients with mild cognitive impairment (MCI) but do not appear to benefit global functioning, according to the results of a new multicentre, randomized trial (Doody et al. Neurology 2009; epublished January 28, 2009).
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Nortriptyline effective in PD-associated depression

 

Depression is a common feature of Parkinson’s disease, with studies reporting a prevalence ranging from 25% to 45% (Ravina et al. Neurology 2007;69:342-347; Lemke et al. J Neurol Sci 2006;248:266-270). However, few randomized controlled trials of depression in PD have been performed and the optimal treatment approach has not been established.

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Stroke reduction with rosuvastatin: the Jupiter Study

 

REPORT FROM THE AHA/ASA INTERNATIONAL STROKE CONFERENCEStatin treatment significantly reduced the number of stroke events versus placebo, according to results from the JUPITER trial presented at the International Stroke Conference (Ridker et al. Abstract 140).
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Adherence and outcomes in stroke

 

REPORT FROM THE AHA/ASA INTERNATIONAL STROKE CONFERENCEA retrospective analysis of data from the Vitamin Intervention for Stroke Prevention (VISP) trial has examined the impact of patient adherence on clinical outcomes (Ovbiagele et al. Abstract P466).
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