Modafinil may reduce physical fatiguability but does not appear to alleviate fatigue symptoms in patients with Parkinsons disease, according to the results of a placebo-controlled pilot study (Lou et al. Clin Neuropharmacol 2009; epublished June 10, 2009).
Neurology
EBV: an association with MS?
November 3, 2009A history of infectious mononucleosis caused by the Epstein-Barr virus (EBV) appears to be associated with an increased susceptibility to MS, according to an analysis by the Canadian Collaborative Study Group (Ramagopalan et al. Neuroepidemiology 2009; 32: 257-262).
Depression not a dementia risk factor
October 20, 2009A prospective community-based observational study reports no apparent association between depression and the development of dementia (Becker et al. Am J Geriatr Psychiatry 2009; 17: 653-663).
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Smoking may increase risk of MS disease progression
October 20, 2009Three new studies have suggested that cigarette smoking increases the risk of progression in patients with relapsing-remitting MS.
One-third of early PD patients show cognitive decline
October 20, 2009A longitudinal study has examined cognitive decline in 106 patients with early Parkinsons disease (mean age 61.2 years). Cognitive decline was assessed using the Mini Mental State Examination (MMSE; mean baseline 27.8) (Kandiah et al. Mov Disord 2009); epublished February 3, 2009.