REPORT FROM THE 2009 AAN ANNUAL MEETING – An internet survey has been used to estimate the global prevalence of chronic migraine, defined as >15 headache days per month and a clinical diagnosis of migraine (Varon et al. AAN 2009; abstract P06.001).
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Neurology
Cortical thinning in Alzheimers disease
June 22, 2009REPORT FROM THE 2009 AAN ANNUAL MEETING – Several recent studies have indicated that cortical thickness measures may be a useful MRI marker to distinguish mild cognitive impairment (MCI) from normal aging (Wang et al. AJNR Am J Neuroradiol 2009; epublished March 11, 2009), identify patients at risk of developing Alzheimers disease (Bakkour et al. Neurology 2009;72:1048-1055), and to differentiate Alzheimers disease from frontotemporal dementia (Du et al. Brain 2007;130(pt 4):1159-1166; free download at http://brain.oxfordjournals.org/cgi/content/full/130/4/1159).
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Estimating duration of work ability with motor symptom onset
June 22, 2009REPORT FROM THE 2009 AAN ANNUAL MEETING – A U.S. study of 1134 consecutive patients with Parkinsons disease has estimated that individuals can continue to work for about 10 years after the onset of motor symptoms (Jasinska-Myga et al. AAN 2009; abstract P06.166).
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Fingolimod in RRMS: results from two trials
June 22, 2009REPORT FROM THE 2009 AAN ANNUAL MEETING – Fingolimod (FTY720), a novel sphingosine 1-phosphate receptor modulator, appears to be effective in patients with relapsing-remitting MS, according to the results from a new phase III trial.
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Predicting depression in early Parkinsons disease
June 9, 2009REPORT FROM THE 2009 AAN ANNUAL MEETING – An analysis of patients in the DATATOP (Deprenyl and tocopherol antioxidative therapy of parkinsonism) trial (Shoulson I. Acta Neurol Scand Suppl 1989;126:171-175) has attempted to identify factors predictive of depression onset (Uc et al. AAN 2009; abstract S23.004).
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