Neurology

Comparing treatments for behavioural and psychological symptoms

 

REPORT FROM THE 9th INTERNATIONAL CONFERENCE AD/PD, PRAGUE, CZECH REPUBLIC, MARCH 11-15, 2009A single-centre open trial in Sweden has compared the use of galantamine and risperidone for the treatment of behavioural and psychological symptoms in dementia (BPSD) (Freund-Levi. AD/PD; 1290).

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Diabetes a risk factor for MCI, Alzheimer’s disease

 

REPORT FROM THE 9th INTERNATIONAL CONFERENCE AD/PD, PRAGUE, CZECH REPUBLIC, MARCH 11-15, 2009 – German researchers have analysed data from the Longitudinal Study on Adult Development and Aging to assess the impact of type 2 diabetes on the development of mild cognitive impairment (MCI) and Alzheimer’s disease (Toro et al. AD/PD; 427; published as Toro et al. J Alzheimers Dis 2009;16: 687-691)). All subjects were born in the period 1930-1932.

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Alzheimer’’s disease and HMG CoA reductase variants

 

REPORT FROM THE 9th INTERNATIONAL CONFERENCE AD/PD, PRAGUE, CZECH REPUBLIC, MARCH 11-15, 2009 Genetic variants in HMG CoA reductase may influence the risk of Alzheimer’s disease, according to the results of a study of French Canadians from Eastern Canada (Legault et al. AD/PD; 1626).

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Predictors of response: results from long-term follow-up

 

REPORT FROM THE 2009 AAN ANNUAL MEETING – Early progression of disability, a high relapse rate and ongoing MRI activity appear to be indicators of an inadequate response to disease-modifying therapy, according to the 15-year follow-up results of the MS Collaborative Study Group pivotal trial of beta-interferon-1a (Avonex) (Bermel et al. AAN 2009; abstract P02.117).
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Prospective trial of vitamin D in MS

 

REPORT FROM THE 2009 AAN ANNUAL MEETING – High-dose vitamin D3 supplementation appears to be well tolerated and significantly reduces T cell reactivity, according to the results of a prospective Canadian trial (Burton et al. AAN 2009; abstract P01.110).
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