A systematic analysis of antiepileptic drug trials has concluded that safety data for pediatric patients is not adequately reported (Anderson & Choonara. Arch Dis Child 2010; 95: 731-738).
Neurology
Negative trial of DHA supplementation in Alzheimer’s disease
January 26, 2011Docosahexaenoic acid (DHA) is an omega-3 polyunsaturated fatty acid that has been shown in vitro and in animal models to alter beta-amyloid accumulation and to have anti-apoptotic activity (Oksman et al. Neurobiol Dis 2006; 23: 563-572). For a recent review see Jicha & Markesbery. Clin Interv Aging 2010; 5: 45-61; free full text at www.ncbi.nlm.nih.gov/pmc/articles/PMC2854051/pdf/cia-5-045.pdf.
Vitamin D and UV exposure during pregnancy/postpartum period
January 26, 2011Two new studies have examined the effect of vitamin D in women during pregnancy and the postpartum period.
CCSVI 2010: The Year in Review
January 18, 2011January 2010:
– Internet blogs, Facebook friends and chatroom klatsches discuss CCSVI following a W-5 news program on the procedure broadcast on November 19, 2009.
– The International Union of Phlebology votes unanimously to include CCSVI lesions in its new guidelines.
– An online petition calling for governments to approve CCSVI collects 12,000 signatures.
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Saliva amyloid proposed as Alzheimer disease biomarker
January 12, 2011A pilot study of potential Alzheimer disease biomarkers has proposed that highly sensitive ELISA testing of amyloid levels in saliva may help to distinguish AD from other types of dementia at an early stage of the disease process (Bermejo-Pareja et al. BMC Neurol 2010; 10: 108).