Provides information on SPMS diagnosis, active and progressive sub-phenotypes, time to SPMS in historical and contemporary cohorts, age and EDSS score as predictors of SPMS, and patients’ symptom that may herald the transition to SPMS.
10 slides
SLIDE LIBRARY
Anti-CD20 therapies – Mechanisms of action
May 25, 2021Provides information on CD20, binding epitopes of anti-CD20 monoclonal antibodies (rituximab, ocrelizumab, ofatumumab, ublituximab) and the effects of anti-CD20 MAbs in multiple sclerosis. Includes slides explaining antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC).
12 slides
SARS-CoV-2 variants
March 11, 2021Summarizes recent data on the UK (B.1.1.7), Brazil (P.1) and South Africa (B.1.351) variants. Also included are the number of variant cases reported in Canada and the U.S. as of March 9, 2021.
9 slides
COVID-19 vaccines and Multiple sclerosis – update
February 26, 2021Updates the February 11 slide deck. Includes data on the immune response to SARS-CoV-2, efficacy data for the Oxford-AstraZeneca vaccine, and updates the vaccine recommendations from the Canadian Network of MS Clinics.
13 slides
COVID-19 vaccines and Multiple sclerosis
February 11, 2021Includes the SARS-CoV-2 life cycle, vaccine targets, COVID-19 vaccines in use and in late-stage development, mRNA vaccine phase III data, and the Canadian Network of MS Clinics’ vaccine guidance.
19 slides