Controversies with revised 2017 McDonald criteria
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Controversies with revised 2017 McDonald criteria
The 2017 revisions to the McDonald criteria introduced three important changes: OCBs could be substituted for dissemination in time (DIT) to arrive at a diagnosis of MS; asymptomatic Gd+ lesions could be used when determining dissemination in space and time; and cortical lesions could be used to support dissemination in space (DIS) (Thompson et al. Lancet Neurol 2018;17:162-73).