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American Academy of Neurology, Vancouver, B.C., 15-21 April 2016
CONGRESS HIGHLIGHTS – WEDNESDAY EDITION Read More
Latest News
Growing evidence of traumatic brain injury as a PD risk factor
April 13, 2016Traumatic brain injury has been an important focus at the American Academy of Neurology annual meeting, and new data are expected at AAN 2016 later this month in Vancouver. Read More
Off-target effects proposed as reason for phase I study death
April 6, 2016Off-target drug effects may be the reason for the phase I accident in France that left one person dead and five others hospitalized (see 1 dead in phase I trial, NeuroSens, January 27, 2016). However, other causes are also being explored by the 12-person Temporary Specialist Scientific Committee (TSSC) set up by France’s Agence national de securité du medicament et des produits du santé (ANSM). Read More
Radiological biomarker proposed for PD
March 30, 2016A number of studies in patients with Parkinson’s disease have reported increased iron concentrations in brain structures, notably the substantia nigra (SN), which may be prognostic of disease severity. One method for assessing iron deposition is to determine the relaxation rate (R2*, the sum of R2 and R2’) on MRI, in which inhomogeneities in the magnetic field due to iron deposition result in a more rapid signal decay and an increase in the relaxation rates. Read More