A number of studies in patients with Parkinson’s disease have reported increased iron concentrations in brain structures, notably the substantia nigra (SN), which may be prognostic of disease severity. One method for assessing iron deposition is to determine the relaxation rate (R2*, the sum of R2 and R2’) on MRI, in which inhomogeneities in the magnetic field due to iron deposition result in a more rapid signal decay and an increase in the relaxation rates. Read More
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Gender differences in frontotemporal dementia
March 16, 2016Few studies to date have specifically examined gender differences in patients with frontotemporal dementia (FTD). A new study has investigated this issue in 26 patients with behavioural-variant FTD (Koros et al. EAN 2015; abstract F2014). Cognitive and behavioural symptoms in 26 males and females were compared based on neuropsychological and behavioural testing and patient history. The scales used were the Neuropsychiatric Inventory (NPI) and the Frontal Behavioral Inventory (FBI). Read More
ECTRIMS 2015
March 9, 2016Dr. Marcelo Kremenchutzky, Director of the Multiple Sclerosis clinic at the London Health Sciences Centre, interviews researchers at the annual meeting of the European Committee for Treatment and Research in MS (ECTRIMS).
Zika virus – New guidelines for managing pregnant women
February 3, 2016Clinical symptoms
Zika virus and pregnancy
Guidelines for clinicians
The U.S. Centers for Disease Control (CDC) has issued guidelines for healthcare providers managing pregnant women at risk of exposure to the Zika virus during the current pandemic (Petersen et al. MMWR Morb Mortal Wkly Rep 2016;65:30-33; free full text at http://dx.doi.org/10.15585/mmwr.mm6502e1). Read More