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Topiramate vs. phenytoin in new-onset epilepsy

December 8, 2010

A 1-month trial comparing topiramate 100 mg/day versus phenytoin (1000 mg on day 1, 300 mg/day maintenance) in 261 patients with new-onset epilepsy has found that the two treatments are comparable. The primary objective of non-inferiority could not be established (Ramsay et al. Epilepsia 2010; 51: 1970-1977). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newslet…

Video game rehabilitation: a Wiiview

November 10, 2010

…fell on her Wii console (Peek et al. Ann R Coll Surg Engl 2008; 90: W9-10; free full text at www.ncbi.nlm.nih.gov/pmc/articles/PMC2647267/?tool=pubmed). Comment: Dr. Selchen: Dr. Saposnik’s very interesting pilot study raises the possibility that gaming may be of value in rehabilitation. This study is of particular interest given the lack of evidence for many rehab interventions. A larger, more definitive study is planned which may open new avenue…

New data on fingolimod in RRMS

October 18, 2010

REPORT FROM THE 26TH CONGRESS OF THE EUROPEAN COMMITTEE FOR TREATMENT AND RESEARCH IN MS (ECTRIMS), GOTHENBURG, SWEDEN, OCTOBER 13-16, 2010 – The oral agent fingolimod consistently reduces relapse rates regardless of disease severity or treatment history, and drug discontinuation is not associated with significant clinical complications, according to new studies and analyses presented at ECTRIMS. Subscribe to read more It takes 30 seconds or logi…

CCSVI: interventions not justified

October 14, 2010

REPORT FROM THE 26TH CONGRESS OF THE EUROPEAN COMMITTEE FOR TREATMENT AND RESEARCH IN MS (ECTRIMS), GOTHENBURG, SWEDEN, OCTOBER 13-16, 2010 – “We should not be using any interventions to treat CCSVI (chronic cerebrospinal venous insufficiency) until we can demonstrate that it has a pathological role,” stated Dr. Giancarlo Comi, Milan, Italy, at a special symposium organized by the European Charcot Foundation. “CCSVI is not a cause of MS,” he said…