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White matter hyperintensities predict cognitive decline

…White matter hyperintensities are a predictor of cognitive decline in relatively healthy older subjects, according to data from the Alzheimer Disease Neuroimaging Initiative (Carmichael et al. Arch Neurol 2010; 67: 1370-1378). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…

MoCA recommended to detect cognitive dysfunction in Parkinson’s disease

…ic Working Group has recommended the Montreal Cognitive Assessment (MoCA) as the most suitable tool to detect mild cognitive impairment (MCI) in patients with Parkinson’s disease (Chou et al. Mov Disord 2010; 25: 2501-2507). The task force further recommended that the MoCA be employed in clinical trials of PD where the primary outcome is not cognitive performance. Subscribe to read more It takes 30 seconds or login using your email address Please…

The J-curve: is lower BP better?

…recommends aggressive blood pressure lowering to prevent cardiovascular outcomes (Chobanian et al. JAMA 2003; 289: 2560-2572; free full text at http://jama.ama-assn.org/cgi/reprint/289/19/2560?ijkey=c099fcb433c2980de606feca9dfb451112a828ed). In its classification scheme, JNC-7 regards BP < 120/80 to be normotensive, and systolic BP 120-139 mmHg or diastolic BP 80-89 mmHg to be pre-hypertensive. The increasing risk of cardiovascular events is consi…

Recovery factors after psychosis identified

…A Norwegian study interviewed a cohort of 255 patients with first-episode psychosis to identify factors associated with better outcomes at five-year follow-up (Albert et al. Schizophr Res 2011; 125: 257-266). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…

Parkinson’s disease and melanoma: no genetic link

…While a number of studies have suggested that Parkinson’s disease and melanoma frequently co-occur, a new study has reported that no genetic link could be found between the diseases. Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…