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Long-term efficacy, safety of DMTs in MS

…ity of recovery was examined in a pooled analysis of 505 patients from the FREEDOMS/FREEDOMS II trials (Reder et al. ECTRIMS 2017; abstract P1186). At 8 years, 54.4% of patients on continuous fingolimod 0.5 mg had achieved CDI or minimal EDSS change, 17.2% had fluctuating EDSS scores, and 28.5% had worsening disability. Similar results were seen in the placebo/fingolimod switch groups: 45% were improved/stable, 22.5% had fluctuating disability sco…

Vortioxetine: Improved work productivity in adults with major depression

…(Schatzberg et al. J Clin Psychiatry 2014;75:1411-1418; free full text at www.psychiatrist.com/JCP/article/_layouts/ppp.psych.controls/BinaryViewer.ashx?Article=/jcp/article/Pages/2014/v75n12/v75n1209.aspx&Type=Article). In the study by Katona and colleagues, elderly subjects (mean age 70.6 years) treated with vortioxetine 5 mg/day showed improved processing speed, verbal learning and memory on cognitive testing (Katona 2012). The reference agent…

Cladribine tablets – Updated efficacy and safety results

…ean Medicines Agency, Summary of product characteristics, August 22, 2017. Free full text at www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/004230/WC500234561.pdf No head-to-head trials have compared cladribine tablets with other disease-modifying therapies. To date, only one preliminary study from the MSBase group has examined this issue using a propensity score-matched analysis (Kalincik et al. ECTRIMS 2017; abstr…

ECTRIMS 2017 SLIDE DECK

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