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MoCA recommended to detect cognitive dysfunction in Parkinson’s disease

 

The task force of the Parkinson Study Group Cognitive/Psychiatric Working Group has recommended the Montreal Cognitive Assessment (MoCA) as the most suitable tool to detect mild cognitive impairment (MCI) in patients with Parkinson’s disease (Chou et al. Mov Disord 2010; 25: 2501-2507). The task force further recommended that the MoCA be employed in clinical trials of PD where the primary outcome is not cognitive performance.

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The J-curve: is lower BP better?

 

The Joint National Committee on Prevention,Detection, Evaluation, and Treatment of High Blood Pressure(JNC-7) recommends aggressive blood pressure lowering to prevent cardiovascular outcomes (Chobanian et al. JAMA 2003; 289: 2560-2572; free full text at http://jama.ama-assn.org/cgi/reprint/289/19/2560?ijkey=c099fcb433c2980de606feca9dfb451112a828ed). In its classification scheme, JNC-7 regards BP < 120/80 to be normotensive, and systolic BP 120-139 mmHg or diastolic BP 80-89 mmHg to be pre-hypertensive. The increasing risk of cardiovascular events is considered to be continuous above 115/75 mmHg.

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