A case-control analysis of data from the Physicians’ Health Study reports that there is insufficient evidence that NSAID use lowers the risk of Parkinson’s disease (Driver et al. Br Med J 2011; epublished January 20, 2011; free full text at www.bmj.com/content/342/bmj.d198.long). The database included 22,007 physicians aged 40-84 years. Cases were matched by age and confounders (comorbidity, indicators for NSAID use).
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Cognition impaired during euthymia in bipolar disorder
October 5, 2011A new study reports that patients with bipolar disorder demonstrate changes in neurocognitive performance, notably in attention, speed of information processing and verbal fluency (Chaves et al. Bipolar Disord 2011; 13: 118-123).
BP and Alzheimer’s disease: results inconclusive
September 21, 2011A systematic review of 18 studies reports that there is insufficient evidence to indicate a causal association between blood pressure and the development of Alzheimer’s disease (Power et al. Epidemiology 2011; 22: 646-659).
Merck drops telcagepant migraine drug
September 21, 2011Telcagepant, an oral calcitonin gene-related peptide (CGRP) receptor antagonist for the treatment of migraine, will not be developed further, according to a statement issued as part of Merck’s second-quarter earnings statement and reported by Dow Jones (www.nasdaq.com/aspx/stock-market-news-story.aspx?storyid=201107290851dowjonesdjonline000416&title=updatemerck-to-cut-up-to-13,000-jobsreports-2q-net-gain).