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‘Breakthrough infection’ uncommon after COVID vaccination

February 24, 2022

…d dose in Canada is variously referred to as a booster or additional dose (www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/page-26-covid-19-vaccine.html). However, some countries now define a full vaccine course as three doses of an mRNA vaccine or two doses of the J&J vaccine; a fourth or fifth dose would be considered boosters. Also, the term ‘breakthrough infection’ has fall…

CLINICAL CASES IN MS – CASE 3: MS-LIKE MRI LESIONS IN A WOMAN WITH MIGRAINE

February 21, 2022

…in CSF (79%); and the presence of Gad+ lesions in the brain (69%). Less common responses were younger age (34%) and the presence of infratentorial lesions (34%). View the video commentary by Dr. Virender Bhan. https://www.youtube.com/watch?v=GpAPi0qezLA Click on the link to view the article (Lebrun C. Rev Neurol (Paris) 2015;171:698-706) cited by Dr. Bhan in the video commentary: www.em-consulte.com/article/1007587/alertePM…

SPMS – Toward earlier diagnosis

February 15, 2022

…PMS. In the validation study, the web-based tool took about two minutes to complete (Ziemssen et al. Med Internet Res 2020; 22:e16932). Included were questions on disease activity, symptoms (intermittent/improving/stable/worsening), and impact of symptoms on ADL. In a recent follow-up survey of physicians and nurses, respondents said the questions were similar to those asked in a regular visit; 85.8% said they would be willing to integrate the too…

From a century ago to a look ahead at 2022

January 26, 2022

…on in children aged 5-11 years (Walter et al. N Engl J Med 2022;386:35-46; free full text at www.ncbi.nlm.nih.gov/pmc/articles/PMC8609605/pdf/NEJMoa2116298.pdf). This year should see additional data on COVID-19 outcomes in MS patients from the Global Data Sharing Initiative and other databases. Of particular interest would be more details about the higher mortality rate that was reported at last year’s ECTRIMS meeting (Prosperini et al. P759. Evan…