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Treatment of non-motor symptoms of PD: MDS recommendations

 

The Movement Disorder Society has presented new recommendations on the treatment of non-motor symptoms of Parkinson’s disease (Seppi et al. Mov Disord 2011;26:S42-S80). The evidence-based review updates recommendations published in 2002 and 2004 (Goetz et al. Mov Disord 2002;17[suppl 4]:S1-S166; Goetz et al. Mov Disord 2005;20:523-539).

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Bipolar I in childhood/adolescence: TEAM trial results

 

The treatment of early-age mania (TEAM) trial randomized 279 treatment-naïve children and adolescents (6-16 years, mean 10.1 years) with bipolar I disorder (manic or mixed phase) to one of three anti-mania medications to assess their comparative effectiveness (Geller et al. Arch Gen Psychiatry 2012;epublished January 2, 2012)

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IFN-beta in CIS: phase III REFLEX results

 

The higher dose of interferon-beta-1a (Rebif; 44 mcg) appears to effective in patients with clinically isolated syndrome (CIS) suggestive of MS, according to the results of the phase III REFLEX trial (Comi et al. Lancet Neurol 2012;11:33-41).

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Treatment of motor symptoms of PD: MDS recommendations

 

The Movement Disorder Society has presented new recommendations on the treatment of motor symptoms of Parkinson’s disease (Fox et al. Mov Disord 2011;26:S2-S41). The evidence-based review updates recommendations published in 2002 and 2004 (Goetz et al. Mov Disord 2002;17[suppl 4]:S1-S166; Goetz et al. Mov Disord 2005;20:523-539).

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