A cross-sectional study in Spain has examined clinical correlates of gait dysfunction in AD patients, with further analyses using volumetric MRI and diffusion tensor imaging (Olazaran et al. J Alzheimers Dis 2013;33:495-505).
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Pilot study of GSK-3 drug tested in AD
February 13, 2013A pilot phase IIa study (NCT00948259) has reported promising effects of tideglusib, a novel inhibitor of glycogen synthase-3 (GSK-3), in 30 patients with mild to moderate Alzheimer’s disease (Del Ser et al. J Alzheimers Dis 2013;33:205-215).
Preventing relapses in schizophrenia: meta-analysis
February 13, 2013Antipsychotic medications reduce relapse risk about 60% compared to placebo, according to the results of a Cochrane meta-analysis (Leucht et al. Lancet 2012;379:2063-2071. The analysis included 65 trials (n=6,493).
RIS: what are the risk factors for CIS/MS?
February 13, 2013There has been little information on the natural history of radiologically isolated syndrome (RIS) since it was first described in 2009 (Okuda et al. Neurology 2009;72:800-805).