Patients with non-tremor-dominant PD demonstrate reduced brain activity in the prefrontal cortex and globus pallidus compared to tremor-dominant PD and healthy controls, according to the results of a functional MRI study (Prodoehl et al. JAMA Neurol 2013;70:100-106).
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Drinking water may improve chronic headache
March 13, 2013A randomized trial has found that increased water intake appears to improve QOL scores in patients with chronic headache (Spigt et al. Fam Pract 2012;29:370-375). A total of 102 patients with chronic headache (>2 moderately intense headaches or >5 mildly intense headaches per month) received usual care (stress reduction, sleep improvement strategies) with or without instructions to drink 1.5 L/day. The primary outcome was change in Migraine-Specific Quality of Life (MSQOL).
Vitamin D and MS: conflicting evidence of clinical benefit
February 27, 2013There are now several studies indicating that vitamin D status affects selected clinical endpoints in MS, but evidence for treatment benefits has been mixed.
Levetiracetam in newly-diagnosed epilepsy: KOMET trial results
February 27, 2013Levetiracetam does not show superiority over standard agents for patients newly-diagnosed with epilepsy, according to the results of the KOMET trial.