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Avoid valproate during pregnancy: guidelines

…ACADEMY OF NEUROLOGY – It is relatively safe for women with epilepsy to become pregnant but valproate use and antiepileptic drug polytherapy should be avoided due to an increased risk of fetal malformations, according to new guidelines developed by the American Academy of Neurology and the American Epilepsy Society. Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the…

Significance of oligoclonal bands in MS: conflicting reports

…Several recent studies have examined the clinical significance of oligoclonal bands (OCB) in cerebrospinal fluid, which are present in about 75-95% of MS patients of European descent. Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…

Parkinson motor score higher with suboptimal adherence

…Medication adherence in ParkinsonΒ’s disease patients may be poor as a result of motor symptoms, complex dosing regimens, the need for multiple medications and patientsΒ’ lack of awareness about the clinical impact of poor adherence. Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…

Phase I/II study of non-myeloablative SCT in RRMS

…o have conducted a phase I/II trial of autologous non-myeloablative hematopoietic stem cell transplantation (SCT) in 21 relapsing-remitting MS patients (Burt et al. Lancet Neurol 2009; epublished January 29, 2009). All subjects had experienced >2 steroid-treated relapses or 1 relapse with Gd-enhancing lesions in the previous 12 months despite treatment with a beta-interferon. Subscribe to read more It takes 30 seconds or login using your email add…