Nortriptyline effective in PD-associated depression


Depression is a common feature of Parkinson’s disease, with studies reporting a prevalence ranging from 25% to 45% (Ravina et al. Neurology 2007;69:342-347; Lemke et al. J Neurol Sci 2006;248:266-270). However, few randomized controlled trials of depression in PD have been performed and the optimal treatment approach has not been established.

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