A number of systematic reviews have investigated the optimal approach in treatment-resistant depression (TRD), but the conclusions are somewhat inconsistent and clinical opinion appears to be evolving. Read More
Latest News
Combining drug and psychotherapy more effective for depression, anxiety
September 24, 2014A new meta-analysis has concluded that combining psychotherapy with pharmacotherapy is more effective than either treatment alone in managing patients with major depression, panic disorder or obsessive-compulsive disorder (Cuijpers et al. World Psychiatry 2014;13:56-67; free full text at www.ncbi.nlm.nih.gov/pmc/articles/PMC3918025/pdf/wps0013-0056.pdf). Read More
New data for daclizumab in MS
September 24, 2014Daclizumab is an IgG1 anti-CD25 monoclonal antibody that blocks IL-2-mediated lymphocyte activation. The drug (Zenapax) was originally used to prevent tissue rejection but was withdrawn by Roche in 2009 due to declining demand. Read More
Environmental factors in MS: Air and vitamin D
September 13, 2014REPORT FROM THE ACTRIMS-ECTRIMS – BOSTON, MA, SEPTEMBER 10-13, 2014 – Few studies have examined the potential impact of ambient air quality and airborne particulates on multiple sclerosis. A decade ago, a study in Finland suggested that the frequency of MS relapses was higher with increasing levels of inhaled particulates (Oikonen et al. Neuroepidemiology 2003;22:95-99). Read More