Sex differences have been reported in Parkinson’s disease, notably with respect to a lower incidence and less severe motor symptoms in females.
For example, in the Oxford PD Disease Center discovery cohort study, males demonstrated a pattern of more symmetrical and severe symptoms in the upper body whereas postural problems were more evident in women (Szewczyk et al. Parkinsonism Relat Disord 2014;20:99-105). Non-motor symptoms of cognitive impairment, REM behaviour disorder, orthostatic hypotension and sexual dysfunction, were more common in men. Read More