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Toward a new standard in MS disease control

October 22, 2014

REVIEWER: Dr. Mark S. Freedman, Director, Multiple Sclerosis Research Unit, The Ottawa Hospital, Ottawa, Canada

Redefining therapeutic efficacy
Conclusions

New data on novel and emerging therapies were the centrepiece of the 2014 joint meeting of the Americas and European Committee for Research and Treatment of Multiple Sclerosis (ACTRIMS/ECTRIMS), with results suggesting that clinical standards are being redefined for optimal disease control in relapsing-remitting multiple sclerosis (RRMS). Read More

Poor adherence to migraine prophylaxis

October 8, 2014

Short-term adherence to migraine prophylaxis is poor, with about one-half of patients stopping their medication within a year, according to the results of a systematic review (Hepp et al. J Manag Care Pharm 2014;20:22-33). Read More

Augmentation in treatment-resistant depression: meta-analyses

October 8, 2014

A number of systematic reviews have investigated the optimal approach in treatment-resistant depression (TRD), but the conclusions are somewhat inconsistent and clinical opinion appears to be evolving. Read More

Combining drug and psychotherapy more effective for depression, anxiety

September 24, 2014

A new meta-analysis has concluded that combining psychotherapy with pharmacotherapy is more effective than either treatment alone in managing patients with major depression, panic disorder or obsessive-compulsive disorder (Cuijpers et al. World Psychiatry 2014;13:56-67; free full text at www.ncbi.nlm.nih.gov/pmc/articles/PMC3918025/pdf/wps0013-0056.pdf). Read More

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