REPORT FROM THE ENS 2008 – Ibudilast (MN-166, AV-411), a nonselective phosphodiesterase inhibitor, may provide some degree of neuroprotection following acute MS lesion formation, according to a retrospective analysis of MRI data from the MN-166 CL-01 study (Gammans et al. Abstract 0191. J Neurol 2008;255(suppl 2): 45).