CLINICAL CASES IN MS – AN OLDER PATIENT WITH STABLE DISEASE

 

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Janet, 58, currently works full-time running an animal grooming business. She is married with two adult children.  She was diagnosed in 1997 with RRMS after presenting with two mild relapses. MRI at that time revealed a low T2 burden of disease. She was initially hesitant about starting treatment. In 2003, she initiated therapy with interferon-beta-1b after experiencing a moderately-severe relapse with some residual disability. EDSS was 1.5.

Between 2003 and 2015, Janet had three relapses with no accumulation of disability. An MRI in 2012 revealed two new lesions. In 2016, Janet reported that she was tired of self-injecting and was switched to dimethyl fumarate. She has been relapse-free for the past five years.  An MRI in 2019 showed two new lesions but MRI has been stable ever since. EDSS has been stable for five years; in November 2022, EDSS score was 2.5 (motor 2, cerebellar 2).

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