The European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) and the European Academy of Neurology (EAN) have published new guidelines on the use of disease-modifying drugs (DMDs) for multiple sclerosis (Montalban et al. Mult Scler 2018; epublished January 1, 2018; free full text at http://journals.sagepub.com/doi/pdf/10.1177/1352458517751049). The groups identified 10 key questions, and issued a series of recommendations based on the level of evidence.

The following is a summary of the groups’ recommendations. Read More

SPECIAL REPORT

7^TH JOINT ECTRIMS-ACTRIMS MEETING – October 25-28, 2017

Teriflunomide
Dimethyl fumarate
Fingolimod
Alemtuzumab Read More

Health Canada has approved cladribine tablets for the treatment of adults with relapsing-remitting multiple sclerosis (RRMS), to reduce the frequency of clinical exacerbations and delay the progression of disability. The drug, marketed as Mavenclad, may be used for newly-diagnosed patients, but is generally recommended in MS patients with an inadequate response or poor tolerability to a prior MS therapy. Read More

Cladribine tablets, a novel intermittent immunosuppressant expected soon in North America, has been shown to be highly efficacious in reducing annualized relapse rates (ARR) and disability progression over a sustained period, according to the most recent data. Read More