The Canadian Network of MS Clinics has updated its COVID vaccine recommendations following a report of a reduced vaccine response in MS patients receiving fingolimod or ocrelizumab (see Few vaccine responders with fingolimod, ocrelizumab, NeuroSens, April 23, 2021). Read More

An analysis of patients in the German MS Register has found that 83% of real-world patients would not have met inclusion/exclusion criteria for entry in a trial of disease-modifying therapies (Jalusic et al. Mult Scler 2021; epublished January 20, 2021). Read More

Most MS patients currently treated with fingolimod or ocrelizumab will fail to mount an immune response to COVID-19 vaccination, according to the results of the first real-world study of vaccine response in MS patients on disease-modifying therapies (DMT) (Achiron et al. Ther Adv Neurol Disord 2021:14:1-8). An adequate vaccine response was seen in cladribine-treated patients. Read More