There is considerable discussion in the media (social and otherwise) about semaglutide (Wegovy), one of a class of drugs now approved for the treatment of obesity. Of further interest is the potential usefulness of these agents in a range of neurodegenerative disorders, including MS, Alzheimer’s disease and Parkinson disease. Read More
Neurology
Putting shared decision-making into practice
February 16, 2023Three elements
Decision aids
Use of patient-reported outcome measures (PROMs)
Switching therapy
SDM: strengths and limitations
The concept of shared decision-making (SDM) has gained momentum in recent years as the preferred approach to MS care. The emergence of SDM two decades ago can be traced back to an acknowledgement of the greater role patients wanted to play in their care decisions, in part due to the recognition that patients’ treatment goals may differ from those of the clinician (Kumar et al. Patient Prefer Adherence 2021;15:1515-1527); and a proliferation of treatments that were similar so that medication choices were preference-sensitive. The advent of social media provided a further spur to patients’ notions of empowerment and participatory medicine (Kantor et al. Neurol Ther 2018;7:37-49). Read More
The end of MS phenotypes?
January 26, 2023The International Advisory Committee on Clinical Trials in Multiple Sclerosis is recommending that the clinical course descriptions of MS – relapsing-remitting (RRMS), secondary-progressive (SPMS) and primary-progressive (PPMS) – be discarded in favour of a more biology-based approach (Kuhlmann et al. Lancet Neurol 2022; epublished November 18, 2022). Read More
MS Awards 2022 – Oddities and Observations
December 9, 2022MS Prodromedary Prize
A study in Saudi Arabia found that the most important risk factor for the development of MS was consumption of camel milk (odds ratio 2.50) (Alkhawajah et al. Neuroepidemiology 2022;56:97-103). Read More
Effectiveness of COVID boosters in MS: an update
November 30, 2022Two recent studies have reported that COVID boosters can increase the humoral response in MS patients during treatment with ocrelizumab or fingolimod. A number of studies have reported that these disease-modifying therapies (DMT) are associated with a blunted humoral response to COVID vaccination (Achiron et al. Ther Adv Neurol Disord 2021;14:17562864211012835. Gallo et al. Neurol Sci 2021;42:3523-3526). Read More
