SPECIAL REPORT
Neurology
High-efficacy DMTs in MS – the year in review
November 14, 2024Cenobamate as adjunctive therapy for partial-onset seizures: a review
October 25, 2024SPECIAL REPORT
Mechanism of action
Efficacy and safety studies
Use of adjunctive cenobamate in practice
Quick poll on epilepsy management
Submit your answers to reveal how your colleagues voted (respondents remain anonymous)
Pregnancy and MS – new data from ECTRIMS
October 17, 2024SPECIAL REPORT
Pregnancy and MS
Effect of treatment on postpartum relapses
Pregnancy outcomes in treated patients
Fetal and neonate drug exposure with ocrelizumab
Quick poll on pregnancy and MS
Submit your answers to reveal how your colleagues voted (respondents remain anonymous)
ECTRIMS update on ofatumumab
October 11, 2024SPECIAL REPORT
While there is a growing consensus on the benefits of initiating treatment with a higher-efficacy (HE) disease-modifying therapy (DMT) in MS, there are a few considerations in clinical practice that need to be addressed. The key issues include the efficacy of HE DMTs relative to lower-efficacy therapies in slowing disability worsening; whether anti-CD20 monoclonal antibody agents (e.g. ofatumumab, ocrelizumab), which primarily target inflammatory disease activity, have an impact on progression independent of relapse activity (PIRA); how switching therapies may optimize outcomes; and whether long-term drug exposure is safe. Read More