REPORT FROM THE WORLD CONGRESS ON TREATMENT AND RESEARCH IN MS – The severity and location of an MS relapse, and the degree of recovery from the attack, will predict the severity and location of subsequent attacks, according to an analysis by Dr. Emmanuelle Waubant, University of California, San Francisco (Waubant E. Abstract 48. Mult Scler 2008;14(suppl 1): S18).
Neurology
Genetic factors may influence tauopathy, AD risk
October 21, 2008REPORT FROM THE ENS 2008 – The tau protein stabilizes microtubules but is believed to contribute to the development of neurofibrillary tangles when it becomes hyperphosphorylated.
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Effect of ibudilast on black holes
October 21, 2008REPORT FROM THE ENS 2008 – Ibudilast (MN-166, AV-411), a nonselective phosphodiesterase inhibitor, may provide some degree of neuroprotection following acute MS lesion formation, according to a retrospective analysis of MRI data from the MN-166 CL-01 study (Gammans et al. Abstract 0191. J Neurol 2008;255(suppl 2): 45).
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Zonisamide pilot study in PD-associated impulse control disorders
October 21, 2008REPORT FROM THE ENS 2008 – Zonisamide (Zonegran) is a sulfonamide anticonvulsant used as an adjunctive therapy in epilepsy.
PROCESS study of spinal cord stimulation: 24-month data
October 8, 2008REPORT FROM THE ENS 2008 – The Canadian PROCESS study compared spinal cord stimulation (SCS) plus conventional medical management (CMM) to CMM alone in 100 patients with predominant neuropathic leg pain secondary to failed back surgery syndrome (Kumar et al. Pain 2007;132:179-188).
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