REPORT FROM THE AMERICAN ACADEMY OF NEUROLOGY – It is relatively safe for women with epilepsy to become pregnant but valproate use and antiepileptic drug polytherapy should be avoided due to an increased risk of fetal malformations, according to new guidelines developed by the American Academy of Neurology and the American Epilepsy Society.
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Neurology
Estimating the lifetime risk of PD
May 5, 2009Researchers at Harvard University have examined a cohort of male physicians (age range 40-84) in the U.S. (n=21,970) to estimate the incidence and lifetime risk of Parkinsons disease (Driver et al. Neurology 2009;72:432-438).
Significance of oligoclonal bands in MS: conflicting reports
May 5, 2009Several recent studies have examined the clinical significance of oligoclonal bands (OCB) in cerebrospinal fluid, which are present in about 75-95% of MS patients of European descent.
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Apathy associated with cognitive decline in AD, MCI
May 5, 2009Two recent studies in France have indicated that apathy may be an indicator of cognitive declines in patients with mild cognitive impairment (MCI), and of functional decline in those with Alzheimers disease.
Parkinson motor score higher with suboptimal adherence
April 21, 2009Medication adherence in Parkinsons disease patients may be poor as a result of motor symptoms, complex dosing regimens, the need for multiple medications and patients lack of awareness about the clinical impact of poor adherence.