Neurology

Phase II trial of novel carbidopa/levodopa formulation

 

A new extended-release formulation of carbidopa/levodopa (CD/LD) appears to be as effective as standard CD/LD in stable patients with Parkinson’s disease, according to the results of a small phase II study (Hinson et al. Clin Neuropharmacol 2009; 32: 189-192).

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Pilot study of modafinil for fatigue in PD

 

Modafinil may reduce physical fatiguability but does not appear to alleviate fatigue symptoms in patients with Parkinson’s disease, according to the results of a placebo-controlled pilot study (Lou et al. Clin Neuropharmacol 2009; epublished June 10, 2009).

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