A new extended-release formulation of carbidopa/levodopa (CD/LD) appears to be as effective as standard CD/LD in stable patients with Parkinsons disease, according to the results of a small phase II study (Hinson et al. Clin Neuropharmacol 2009; 32: 189-192).
Neurology
Higher diastolic BP associated with cognitive impairment
November 3, 2009Higher diastolic blood pressure levels appear to be associated with impaired cognitive status, according to an analysis of subjects enrolled in the REGARDS study (Tsivgoulis et al. Neurology 2009; 73: 589-595).
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Pilot study of modafinil for fatigue in PD
November 3, 2009Modafinil may reduce physical fatiguability but does not appear to alleviate fatigue symptoms in patients with Parkinsons disease, according to the results of a placebo-controlled pilot study (Lou et al. Clin Neuropharmacol 2009; epublished June 10, 2009).
EBV: an association with MS?
November 3, 2009A history of infectious mononucleosis caused by the Epstein-Barr virus (EBV) appears to be associated with an increased susceptibility to MS, according to an analysis by the Canadian Collaborative Study Group (Ramagopalan et al. Neuroepidemiology 2009; 32: 257-262).
Depression not a dementia risk factor
October 20, 2009A prospective community-based observational study reports no apparent association between depression and the development of dementia (Becker et al. Am J Geriatr Psychiatry 2009; 17: 653-663).
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