MS patients treated with a beta-interferon are often advised to self-inject before going to bed to improve the tolerability of flu-like symptoms. But a study in France has found that patients with intolerable side effects may benefit from a switch to morning injections (Nadjar et al. Clin Neurol Neurosurg 2011; 113: 316-322).
Neurology
Little evidence to support non-antiepileptic drug in trigeminal neuralgia
September 7, 2011A systematic review concludes that there is insufficient evidence demonstrating significant benefit from non-antiepileptic drugs in trigeminal neuralgia despite their widespread use since the 1970s (Yang et al. Cochrane Database Syst Rev 2011, Jan 19;1:CD004029).
Call for guidelines on managing PD patients in hospital
September 7, 2011Motor and psychiatric complications are frequent reasons for hospital admission of patients with Parkinson’s disease and guidelines are needed for the management of in-hospital care, according to a National Parkinson Foundation working group (Aminoff et al. Parkinsonism Relat Disord 2011; 17: 139-145).
Beta-amyloid accumulation prior to cognitive impairment: longitudinal data
August 24, 2011Beta-amyloid deposition is a slow process that can be identified in subjects without cognitive impairment, according to the results of a three-year longitudinal study (Villemagne et al. Ann Neurol 2011; 69: 181-192).
No gain with higher dose of glatiramer acetate
August 24, 2011A higher dose of glatiramer acetate appears to be well tolerated but does not provide improved efficacy over standard dosing, according to the results of the FORTE study (Comi et al. Ann Neurol 2011; 69: 75-82).