Better prognosis for OCB-negative patients


Highlights of the 29th Congress of the European Committee for Treatment and Research in MS (ECTRIMS), Copenhagen, DK, October 2-5, 2013 – MRI has largely eclipsed CSF analysis of oligoclonal bands (OCB) as the preferred paraclinical assessment to support a diagnosis of MS and there are conflicting reports on the prognostic significance of OCB results. Some studies have found that OCB-negativity is prognostic of a more favourable long-term outcome (Joseph et al. J Neurol Neurosurg Psychiatry 2009;80:292-296; Mandrioli et al. J Neurol 2008;255:1023-1031).

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