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MSToronto 2026 Highlights – Wednesday, October 21, 2026

 

The 10th Joint meeting of the Americas and European Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS-ECTRIMS)

The following summarizes some of the highlights from Day 1 of MSToronto 2026.

MS risk with infectious mononucleosis
sNfL elevation postpartum
PRLs contribute to treatment failure
Update on frexalimab
Daratumumab effective in AQ4-IgG+ NMOSD
One-quarter of MS patients are untreated
Clinical tip of the day
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Ofatumumab 2026 – update on real-world effectiveness

 

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Patient satisfaction with high-efficacy therapies
Switching therapies
Real-world impact on PIRA

Over 12,000 MS patients in Canada have been treated with ofatumumab, an anti-CD20 monoclonal antibody administered by self-injection, since it was authorized for use five years ago. A Canadian study has now examined patient acceptance of treatment in an analysis of patient support program (PSP) data (Selchen et al. Mult Scler Relat Disord 2026:107:106976). A total of 5436 of 6377 patients in the database met inclusion criteria. Treatment persistence was 96.94% at 12 months, 95.02% at 24 months and 92.26% at 36 months. The most common reasons for treatment discontinuation were side effects (0.9%), conception/pregnancy (0.5%) and patient request (0.5%). Read More

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